EH, NG, SR contributed to the interpretation

MCC950 solubility dmso of data and to the writing of the paper. YN conceived the research program focused on regulation of egg innate immunity. He was involved in the strategy, the experimental design, data interpretation and was fully involved in the writing of the paper. “After the publication of our study [1], we became aware that the mutations in the HDAC inhibitor quinolone resistance-determining region (QRDR) of the gene grlA were incorrectly described for some of the Staphylococcus aureus clinical isolates studied in this work. ATCC25923EtBr – WT WT 200 25 12.5 C188-9 solubility dmso 1 0.25 0.25 2 0.25 0.25 64 n.d. SM1 A2 S80Y/E84G S84L 16 4 4 128 32 64 512 128 256 256 64 64 SM10 A4 S80Y/E84G S84L 16 2 4 128 64 64 512 128 128 128 64 64 SM14 A3 S80Y/E84G S84L 16 4 4 256 32 128 1024 128 256 256 64 64 SM17 A4 S80Y/E84G S84L 16 4 4 256 64 64 1024 256 512 256 64 64 SM25 A1 S80Y/E84G S84L 8 2 4 128 32 64 512 64 128 256 32 64 SM27 A4 S80Y/E84G S84L 16 4 4 256 32 64 512 128 256 256 64 64 SM43 A1 S80Y/E84G S84L 16 2 4 128 64 64 512 128 128 512 256 64 SM46 A1 S80Y/E84G S84L

16 4 4 128 64 64 512 128 256 128 64 64 SM47 A1 S80Y/E84G S84L 8 2 4 256 32 64 512 128 256 256 Urocanase 64 64 SM48 A1 S80Y/E84G S84L 8 4 4 256 32 64 512 128 256 256 64 64 SM50 B1 S80F/E84K S84L 8 1 2 64 16 16 256 32 64 128 64 64 SM52 C1 S80Y S84L 16 1 2 16 8 8 64 32 32 128 32 64 SM2 B2 S80F/E84K S84L 8 2 2 32 16 16 128 32 32 64 16 64 SM3 E1 S80F/E84G S84L 1 1 1 16 8 8 64 32 32 64 16 16 SM4 E2 S80F S84L 4 2 1 8 8 8 64 32 32 64 32 64 SM5 E3 S80F/E84G S84L 4 2 1 32 16 16 128 64 64 64 32 32 SM6 A5 S80F E88K 4 2 1 16 16 16 64 32 32 64 32 32 SM7 E1 S80F S84L 2 2 1 8 8 4 64 32 32 128 32 64 SM8 A5 S80F E88K 4 2 1 16 8 16 128 64 64 128 32 64 SM12 E1 S80F S84L 2 2 1 16 8 8 64 32 32 128 32 64 SM16 A6 S80F E88K 4 2 1 16 16 16 128 32 64 64 32 64 SM22 A1 S80Y/E84G S84L 8 4 4 128 16 32 512 128 128 64 32 64 SM34 D1 S80F/E84K S84L 4 2 2 64 16 32 64 16 32 32 16 32 SM36 E1 S80F S84L 4 2 2 16 8 8 64 16 32 128 32 64 SM40 E1 S80F S84L 8 4 4 32 32 32 512 128 128 16 8 16 aIsolates in bold correspond to the EtBrCW-positive isolates.