There was no statistically significant difference between the latter two time brackets. (C) 2013 Elsevier Ireland Ltd. All rights reserved.”
“This

study aimed to evaluate the action of Brazilian green Akt inhibition propolis (5%) topic use on cutaneous wound healing in rats, by inflammatory cell counting. Ten Wistar rats were separated in groups 24 h and 72 h, were trichotomized under anesthesia on cervical-dorsal region, and 2 wounds were provoked with a biopsy punch (5 mm diameter). Left wound underwent Brazilian green propolis topic treatment, and right wounds received nothing. Tissue samples were processed for light microscopy with hematoxilineosin., and leucocytes, macrophages and fibroblasts were counted using a histometric reticule in ocular lens. In both groups, within 24 and 72 h evolution, treated wounds demonstrated significant bigger means for leucocytes, macrophages and fibroblasts. Brazilian green propolis resulted in inflammatory cell quantity increase, suggesting its action on tissue repair process.”
“In 1908 the skin hospital and dermatology becomes independent from

internal medicine. Since this time the hospital has been the most important institution for patients with skin diseases. Whereas in the first half of the century the medical attention of the syphilitic patients come to the fore, the skin hospital developed in the second half as a modern hospital for all the facet of dermatology. The Selleckchem PD0332991 chairs of AZD6244 ic50 dermatology formed its

profile in each case. After more than 100 years a new skin hospital will be build for the first time.”
“Objective: There is no treatment established for congenital sensorineural hearing loss because the majority of the cases are hereditary. Although congenital sensorineural hearing loss is thought to be hereditary, this hearing loss occur postnatally. We hypothesized that the transplantation of MSCs (mesenchymal stem cells) to the cochlea would be an effective therapy for stopping or delaying the progression of sensorineural hearing loss in childhood.

Methods: Cultured mouse MSCs were labeled with EGFP (enhanced green fluorescence protein) using retroviruses. EGFP-MSCs were transplanted into the posterior semicircular canal of mice at 2-3 weeks (young group) and 24-26 weeks (adult group) of age by a novel perilymphatic perfusion technique. Engraftment of MSCs was evaluated immunohistologically at 1 week and 2 weeks after transplantation.

Results: In young mice, migrated MSCs were detected in the cochlea tissue by immunofluorescence for EGFP and by immunohistochemistry for fibronectin. The differentiation of migrated MSCs into fibrocyte-like cells was demonstrated by immunofluorescence for connexin 26. There were no adverse effects on auditory function by MSC transplantation, and the auditory brain stem responses threshold did not significantly shift after surgery.