Basal hemoglobin was significantly lower in CI-AKI patients while Mehran score, contrast medium (CM) volume, contrast ratio (CM volume / maximum contrast dose) and ratio glomerular filtration rate (CM volume / GFR) were significantly higher. Multivariate analysis selected
a higher contrast ratio as a factor independently associated with a higher risk of CI-AKI which otherwise appeared to be lower with increasing basal hemoglobin.
Conclusions: The incidence of CI-AKI after CA or PCI was higher in patients with CKD associated with diabetes. Lower levels of basal hemoglobin appeared to be related to a higher risk of CI-AKI, and contrast media volume, especially if exceeding the dose adjusted for renal function, was a strong modifiable risk factor for CI-AKI.”
“Objective: To psychometrically refine a standardized scale for identifying those lifestyle changes that were most likely to contribute to anxiety and depression among prostate GW786034 cancer (PCa) patients.
Methods: Three hundred and eighty-one PCa patients who had received their initial diagnosis between one and 96 months completed a survey of background variables, anxiety and depression inventories and the
36-item Effects of Prostate Cancer upon Lifestyle Questionnaire (EPCLQ).
Results: Levels of anxiety (24%) and depression (26%) were similar to those previously GSK621 order reported for PCa patients. The EPCLQ was GS-9973 shown to have satisfactory psychometric properties and significantly predicted anxiety and depression scores and the presence of psychological clinicity among this sample. Factor analysis of the EPCLQ showed that adverse emotions and social withdrawal, plus
loss of cognitive ability, were the most powerful predictors of fear, physiological arousal, discomfort and pain factors underlying anxiety; these factors also predicted pessimism and fatigue factors underlying depression.
Conclusions: The EPCLQ was shown to be a reliably sound and valid instrument for assessing important lifestyle changes that predict anxiety and depression among PCa patients. In addition, links between receiving a diagnosis and treatment for PCa and development of psychosocial disturbance via emotional negativity, decreased cognitive performance and withdrawal from others appear to warrant further investigation. Copyright (C) 2009 John Wiley & Sons, Ltd.”
“Introduction: Vitamin D insufficiency contributes to calcitriol (1,25D) reduction in chronic kidney disease (CKD). Since CKD patients on conservative therapy (CRF) mostly develop, whereas transplant (TX) patients possibly recover from, secondary hyperparathyroidism (SH), we hypothesized a different efficiency of vitamin D hydroxylation in these 2 clinical conditions.
Methods: We compared the impact of reduced 25-hydroxyvitamin D (25D) on circulating 1,25D in 111 CRF (mean age 63 +/- 15 years; estimated glomerular filtration rate [eGFR] 36.4 +/- 22.