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“Background: Chronic renal insufficiency (CRI) is a growing global problem. PTA can be performed without nephrotoxic contrast, utilizing Doppler-ultrasound (Duplex) guidance. Duplex-guided infra-inguinal interventions and access-related interventions have been reported. Duplex-guided

LY2109761 purchase iliac interventions have not been performed to any extent because of the anatomic location. In our study we evaluated the safety and efficacy of Duplex-guided percutaneous transluminal angioplasty (DuPTA) in iliac arteries.

Methods: From June 2012 until February 2013, 31 patients (35 iliac lesions), underwent DuPTA. Indications ranged from Rutherford 3 to 5. Preoperative evaluation

included Ankle Brachial Index (ABI), Duplex and MRA. Procedural success was defined as crossing the lesion with a guidewire and dilating or stenting the lesion. Clinical success was defined as 50% reduction in peak systolic velocity (PSV) or clinical improvement. PSV was evaluated after PTA, then at 2 weeks. learn more Clinical results were assessed 2 weeks after the procedure.

Results: Procedural success was achieved in 94% of patients (33/35), all of whom also had clinical success. Post-procedural PSV reduction showed an average improvement of 63% (431 cm/s to 153 cm/s). Mean preoperative ABI was 0.72 and improved to 0.88 postoperatively.

Conclusions: PTA using Duplex-guidance in significant iliac stenosis is a safe method with major advantages in patients at high risk for developing contrast-induced nephropathy. (C) 2013 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.”
“We

aimed to evaluate the incidence of adverse drug reactions (ADRs) at a hospital, determine the variation in the incidence of ADRs between genders and among age groups, and determine the pharmacological class most often involved in ADRs. A longitudinal prospective study was conducted over a period of 5 months by using an active search in all hospital units. Four hundred forty-six patients were CFTR inhibitor followed during their hospitalization; 103 showed ADRs, resulting in a 23% overall incidence. Suspected ADRs were identified in 136 patients. From this group of patients, 9 reactions were classified as definite (6.6%), 77 as probable (56.6%), and 50 as possible (36.8%). Female gender, patient age less than 65 years, and hospitalization in the Gynecology and Obstetrics Ward were factors associated with a higher incidence of ADR development. The active search is a suitable instrument for assessing the incidence of ADRs in the hospital.”
“Background:

Few data exist regarding antegrade selective cerebral perfusion (ASCP) and its application in newborn and juvenile patients.