EQUIPT has a dedicated work package on dissemination of findings. The ROI tools will be available for Crenolanib public download through the project’s website (http://equipt.ensp.org)

together with the accompanying User Guide, Technical Reports and worked-out examples. This will form the part of e-learning resources. The major analytical findings will be disseminated through peer-reviewed publications in scientific journals, presentations in conferences, policy briefs and media briefs. Status of study EQUIPT is a 3-year project that started on 1 October 2013 and will end on 30 September 2016. Discussion EQUIPT is a rare multidisciplinary study designed to test the transferability of economic evidence

around tobacco control and will provide evidence-based, practical and customisable ROI tools to actual decision-makers. The findings are expected to promote and disseminate the ROI methods and results to foster evidence-driven decision-making on comprehensive tobacco control across Europe. The primary aim of transferring comparative effectiveness data to other countries is to make timely and sensible policy recommendations, even in the absence of relevant evidence for the country of interest. This is especially beneficial for countries with fewer analytical resources, where there is a lack of relevant input data to adapt the ROI model and in which there is a higher potential

to save life years from tobacco control and quit support strategies.12 There is a limited understanding of the causes of variability in cost-effectiveness data, and this presents a key barrier to the transferability of the economic evaluation results.9 27 Some authors suggest that “there is a lack of empirical studies which prevents stronger conclusions regarding which transferability factors are most important to consider and under which circumstances.”11 Nevertheless, the transfer of evidence to other countries may be possible if: (1) we identify those factors which cause the most variability in the relative success of tobacco control and quit-support strategies across countries and (2) the countries of interest are appropriately reflected in the existing data.10 Adapting an economic model may GSK-3 require an evaluation of those model components that are similar across countries (core components) and those that vary between countries (country-specific components). For example, the EUnetHTA programme “attempt[s] to define and standardise elements of an HTA” by dividing relevant information on the technology under assessment “into standardised pieces, each of which describing one or more aspects of the technology that is likely to be useful when considering the adoption or rejection of the technology.