Olympus has similar software function (express mode) and we are aware of a single relevant study with very similar results[113]. Table 8 Studies looking at the clinical validity of QuickView, feature of capsule endoscopy reading software, in small-bowel capsule endoscopy In the last few years, Given?Imaging Ltd., through a collaboration with Fujinon HTC Inc., Japan introduced the electronic chromo-endoscopy (Fujinon Intelligent Chromo Endoscopy, FICE) in the field of capsule enteroscopy. Data available thus far, show that application of FICE in SBCE videos, leads to improved image quality and definition of the surface texture of small-bowel lesions (Table (Table99)[114-120]. Although this seems to facilitate the detectability of small-bowel findings, it is still under question whether it proves to be clinically significant[121].
Similar function from Olympus Inc., shows promising results[122]. Table 9 Studies looking at the clinical validity of Fujinon? intelligent chromoendoscopy enhancement/Blue mode, feature of capsule endoscopy reading software, in small-bowel capsule endoscopy WHAT��S NEW ON THE FIELD OF SMALL-BOWEL CAPSULE ENDOSCOPY? As aforementioned, there are differences among different capsule models (Table (Table1).1). Since its introduction in clinical practice in 2001, CE technology has been significantly. For instance, battery life is longer, image capture frame rate has increased, angle of view is now wider, light control has been optimized, and many real time viewing systems are now available. Nevertheless, these impressive advancements, do not allow overcoming the main current limitation of CE, i.
e., uncontrolled propulsion; CE relies totally on natural bowel peristalsis, i.e., it still remains a rather ��passive�� diagnostic technique. Several research groups are working to design brand new capsules able to actively move or to be remotely manoeuvred through their descent in the small bowel[123]. These new capsules would allow not only recognizing a small bowel lesion but also, in a near future, to collect targeted tissue samples or to deliver drugs (Table (Table1010)[124-141]. Table 10 Experimental and models in development for capsule-endoscopy the future? CONCLUSION Since CE introduction Anacetrapib in clinical practice in 2001, over 1500 papers, focused on SBCE, have been published (PubMed search 17/03/2012; keyword term: ��small bowel capsule endoscopy��; available from: http://www.ncbi.nlm.nih.gov/pubmed/?term=small+bowel+capsule+endoscopy). Out of those, < 20% are clinical trials; case reports and reviews account for about 40% of published evidence.