Study Design: Retrospective chart review. Setting: Four hundred and sixty-six patients with chronic non-cancer pain referred to a behaviorally based pain program in a community see more health system. Methods: Data collected included pain intensity and level of pain interference (Brief Pain Inventory), pain duration, pain site, depression level (Beck Depression Inventory Fast Screen for Medical Patients), anxiety (Beck Anxiety Inventory), personal and family psychiatric and substance use disorder history, level of isolation, and demographic data. Univariate and logistic regression analyses

were performed. Results: Results showed a high rate of suicidal ideation in this patient population (28%). Univariate analyses stratified by level of suicide (no suicidal ideation or passive/active suicidal ideation) revealed statistically significant group differences on pain location (extremity P = 0.046, generalized P = 0.047), work disruption (P = 0.049), social withdrawal (P smaller than 0.001), pre-pain history of depression (P smaller than 0.001), family https://www.selleckchem.com/products/VX-680(MK-0457).html history of depression (P smaller than 0.001), and history of sexual/physical abuse (P smaller

than 0.001). Logistic regression revealed that history of sexual/physical abuse (Beta = 0.825; P = 0.020; OR = 2.657 [95% CI = 1.447 - 4.877]), family history of depression (Beta = 0.471; P = 0.006; OR = 1.985 [95% CI = 1.234 - 3.070]), and being socially withdrawn (Beta = 0.482; P smaller than 0.001; OR = 2.226 [95% CI = 1.431 - 3.505]) were predictive of suicidal ideation. Limitations: Measure of depression was not included in data analysis to reduce effect of colinearity. Also the study population was a specialty pain clinic allowing for possible subject selection bias. Conclusions: Results of this study are consistent with the find more prevailing literature on pain and suicide demonstrating a high prevalence of suicidal ideation in the chronic pain population. Novel predictive variables were also identified that will provide the basis for developing a risk stratification model that

can be further tested prospectively in chronic pain patients.”
“PurposeTo evaluate the feasibility of SWIFT with variable flip angle (VFA) for measurement of T-1 relaxation time in Gd-agarose-phantoms and osteochondral specimens, including regions of very short T-2*, and compare with T-1 measured using standard methods MethodsT(1)s of agarose phantoms with variable concentration of Gd-DTPA(2-) and nine pairs of native and trypsin-treated bovine cartilage-bone specimens were measured. For specimens, VFA-SWIFT, inversion recovery (IR) fast spin echo (FSE) and saturation recovery FSE were used. For phantoms, additionally spectroscopic IR was used. Differences and agreement between the methods were assessed using nonparametric Wilcoxon and Kruskal-Wallis tests and intraclass correlation.