Vet Microbiol 2010,145(3–4):273–278.PubMedCrossRef 16. Nurmi E, Rantala M: New Aspects of Salmonella Infection in Broiler Production. Nature 1973,241(5386):210–211.PubMedCrossRef 17. Leplae R, Geeraerts D, Hallez R, Guglielmini J, Dreze P, Van Melderen
L: Diversity of bacterial type II toxin-antitoxin systems: a comprehensive RG7112 search and functional analysis of novel families. Nucleic Acids Res 2011,39(13):5513–5525.PubMedCentralPubMedCrossRef 18. Baranyi J, Roberts TA: A Dynamic Approach to Predicting Bacterial-Growth in Food. Int J Food Microbiol 1994,23(3–4):277–294.PubMedCrossRef 19. Lenski RE: Quantifying fitness and gene stability in microorganisms. Biotechnology 1991, 15:173–192.PubMed 20. San
Millan A, Garcia-Cobos S, Escudero JA, Hidalgo L, Gutierrez click here B, Carrilero L, Campos J, Gonzalez-Zorn B: Haemophilus find more influenzae Clinical Isolates with Plasmid pB1000 Bearing bla(ROB-1): Fitness Cost and Interspecies Dissemination. Antimicrob Agents Ch 2010,54(4):1506–1511.CrossRef 21. Poole TL, Brichta-Harhay DM, Callaway TR, Beier RC, Bischoff KM, Loneragan GH, Anderson RC, Nisbet DJ: Persistence of Resistance Plasmids Carried by Beta-Hemolytic Escherichia coli When Maintained in a Continuous-Flow Fermentation System Without Antimicrobial Selection Pressure. Foodborne Pathog Dis 2011,8(4):535–540.PubMedCrossRef 22. Bleicher A, Schofl G, Rodicio MD, Saluz HP: The plasmidome of a Salmonella Dapagliflozin enterica serovar Derby isolated from pork meat. Plasmid 2013,69(3):202–210.PubMedCrossRef 23. Diekmann O, Heesterbeek JAP, Diekmann O, Heesterbeek JAP: Mathematical epidemiology of infectious diseases: model building, analysis, and interpretation. Chichester;
New York: John Wiley; 2000. 24. Wan Z, Varshavsky J, Teegala S, McLawrence J, Goddard NL: Measuring the Rate of Conjugal Plasmid Transfer in a Bacterial Population Using Quantitative PCR. Biophys J 2011,101(1):237–244.PubMedCentralPubMedCrossRef 25. Andrup L, Andersen K: A comparison of the kinetics of plasmid transfer in the conjugation systems encoded by the F plasmid from Escherichia coli and plasmid pCF10 from Enterococcus faecalis. Microbiol-Uk 1999, 145:2001–2009.CrossRef 26. Lundquist PD, Levin BR: Transitory Derepression and the Maintenance of Conjugative Plasmids. Genetics 1986,113(3):483–497.PubMedCentralPubMed Competing interest The authors declare that they have no competing interests. Authors’ contribution EF conceived the study, performed the mathematical modelling and statistical analyses, and drafted the manuscript. AvE performed the experiments. CD participated in the design of the experiments and supported the execution of the experiments. HvR participated in the design of the study, coordinated the project and helped to draft the manuscript. AS conceived the study and participated in the design of the study.